Every time I look in the mirror, I notice a wrinkle between my eyebrows. Even if you are not angry, you may be told that you look “scary” or "grumpy. The wrinkles between the eyebrows can easily become deeply etched due to facial habits and aging, making you look older than you actually are or giving the impression that you are angry.
Botox between the eyebrows is attracting attention from those who suffer from such wrinkles between the eyebrows. By injecting a small amount of Botox, the movement of the facial muscles is relaxed and the wrinkles between the eyebrows are made less noticeable.
In this article, we will provide you with a summary of information you should know when considering Botox between the eyebrows, including its effectiveness, duration, amount injected, pain, and other information you need to know when considering the procedure.
What is Botox Between the Eyebrows? Principle of working on expression wrinkles

First, let us explain in detail how Botox between the eyebrows works and what kind of changes it brings about.
Wrinkles between the eyebrows are often caused by “facial expressions.
It is believed that wrinkles between the eyebrows are often caused not only by aging, but also by the habits of daily facial expressions. People tend to naturally pull down the skin between the eyebrows when they are angry, concentrating, or feeling dazzled, creating vertical creases between the eyebrows.
The muscles that work in this process are the wrinkle brow muscles, which are located on the inside of the eyebrows, and the nasal root muscles, which are small triangular muscles located near the base of the nose. The repetitive movement of these muscles over the years causes the skin to fold and eventually carve deep wrinkles.
When the skin is young, wrinkles will naturally disappear if the facial expression is restored due to the skin's elasticity. However, as we age, the collagen and elastin that support skin elasticity decrease, making it difficult for wrinkles to return once they have formed. It is a fact that many people suffer from wrinkles between the eyebrows, as they can give a stern impression of constantly furrowing the brows.
Botox (botulinum toxin preparation) action
Botox, in general, is a drug composed primarily of a naturally occurring protein called botulinum toxin (botulinum toxin). It works by temporarily blocking the signal transmission between nerves and muscles, thereby reducing excessive muscle contraction.
This can be used to reduce the progression of wrinkles or reduce the appearance of wrinkles that have already formed. In particular, it is said to be highly effective for people who have “wrinkles in the early stages of development” or “wrinkles that appear only when facial expressions are moved.
In addition, regular treatment can help prevent wrinkles in the future, making it one of the procedures of choice for people of all ages at Vivi Clinic in Bangkok, Thailand. Furthermore, since the procedure can be performed with injections and there is almost no downtime, it is an easy challenge for those who are new to cosmetic medicine or those who are not comfortable with incisional surgery.
How long does it take to become effective and how long does it last?
The effect appears 2-3 days after the procedure and stabilizes in about 2 weeks. The duration of the treatment is about 3 to 6 months, but regular treatments make it easier to maintain a wrinkle-resistant state. The duration of the treatment tends to be longer with regular treatments, and the more times you have the treatment, the easier it will be for you to feel the effects of “preventing the appearance of aging”.
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Guidelines for Botox injections at Bibi Clinic that you need to know about.

Here is a more specific explanation of the actual Botox treatment between the eyebrows that we perform at Bibi Clinic.
Two types of formulations used at Bibi Clinic
Bibi Clinic offers the following two types of formulations. The most suitable formulation will be proposed after the doctor examines the condition of the wrinkles between the eyebrows by listening to your requests and concerns in detail during the counseling session.
[Allergan: Botox Vista
FDA (U.S. Food and Drug Administration) approved Botox product manufactured by Allergan Inc. in the United States. It boasts the top market share in the world and is highly regarded for its quality, safety, and long-lasting effects.
Made in Korea: Nabota
Manufactured by a major Korean pharmaceutical company. The formulation has been approved by the U.S. FDA and the Korean KFDA (Food and Drug Administration) and is recognized for its safety. It is chosen by those who want to have regular treatments because of its high purity and stable quality as well as excellent cost performance.
<Bibi Clinic Botox Injection Price List
| Nabo | 1 part | 2,980B |
| 50U | 5,980B | |
| 100U | 11,960B | |
| Allegan | 50U | 16,800B |
| 100U | 29,800B |
How many units should be injected between the eyebrows?
The number of units of Botox injected between the eyebrows varies from person to person depending on the strength and usage of the muscles and the depth of the wrinkles, but Bibi Clinic recommends around 6 to 10 units. Injections are generally injected in small amounts in 5 to 6 locations, including the base of the left and right eyebrows, above the eyebrows, and in the center between the eyebrows.
At Bibi Clinic in Bangkok, Thailand, we place great importance on achieving natural-looking results that bring out the patient's natural facial expressions. Before the procedure, we ask patients to actually move their eyebrows to carefully check muscle movement, wrinkles, left-right differences, and the way the eyebrows rise. We then precisely determine which muscles should be affected and by how much, and design the optimal injection amount.
These subtle designs prevent unnatural results such as "wrinkles disappear but the expression is stiff" or "the eyebrows droop and look heavy," and achieve beautiful brows with natural movement.
In addition, we recommend a “step-by-step” approach, in which we do not apply too much pressure at one time, but rather gradually adjust the facial features. By preventing too much effect in the first treatment, you can feel the changes while maintaining your own facial balance more naturally.
If the effect is not as strong as expected, or if you have any concerns during the process, we offer free touch-ups (additional injections). Please experience the natural finish that Japanese people prefer in Bangkok, Thailand.
How painful is Botox between the eyebrows? Pain Management by Bibi Clinic

Botox is painful? is one of the most common questions we receive from patients who are undergoing Botox for the first time. At Vivi Clinic in Bangkok, Thailand, we have taken various measures to minimize the pain so that our patients can undergo the procedure with as much comfort as possible.
Actual pain during treatment
Botox injections between the eyebrows cause a stinging pain when the needle is inserted. Although the pain varies from person to person, many people say that it was not as painful as they expected. The treatment time is very short, about 10 minutes, so the amount of time you feel pain is limited.
Bibi Clinic's 3 Pain Reduction Techniques
- Use of ultrafine needles
We use an ultrafine needle, thinner than a hair. The use of this special needle minimizes damage to the skin, resulting in less internal bleeding and pain. - Use of anesthetic cream (optional)
For those who are particularly sensitive to pain or anxious, we recommend applying an anesthetic cream before the procedure. By allowing the anesthetic cream to penetrate the skin for 20 to 30 minutes, the stinging pain of the needle insertion will be less noticeable. - Quick and accurate procedures by experienced physicians
The pain sensation varies greatly depending on the injection technique. Doctors at Bibi Clinic in Bangkok, Thailand receive regular technical training from BIANCA CLINIC in Tokyo, and have mastered accurate and quick injection techniques. The reliable and precise technique shortens the time required for injection and minimizes pain as a result.
Frequently asked questions about Botox between the eyebrows

In a foreign country like Bangkok, Thailand, it is difficult for Japanese people to take the first step, especially when they imagine the "what ifs" after the procedure. Although Botox between the eyebrows is a relatively easy procedure, many people are concerned about the risks and changes in facial expressions.
Here we will answer some of the most frequently asked questions that we actually receive from Bibi Clinic patients.
Q: How long is the downtime for Botox between the eyebrows?
A. There is almost no downtime. The area where the needle is inserted may become temporarily red, but in most cases it will resolve spontaneously within a few hours to three days, and recovery is smooth. In rare cases, internal bleeding may occur, but it can be concealed with makeup. You can wash your face and apply makeup on the same day of the procedure, and can return to your daily life immediately.
Q: I heard that Botox makes the eyes look smaller or heavier.
A. Depending on the position and balance of the amount of Botox injected between the eyebrows, the movement of the muscles that raise the eyebrows may be temporarily suppressed, causing the eyes to feel heavy or look smaller.
Although this can happen depending on the skill and experience of the practitioner, you can trust that the doctors at Bibi Clinic have honed their skills under the supervision of Bianca Clinic, which has an established reputation for Botox.
Q: Can I have hyaluronic acid injections together?
A. Yes, they can be combined. Botox between the eyebrows is a treatment that "suppresses muscle movement" and hyaluronic acid is a treatment that "supplements volume. Since they have different purposes, a smoother result can be expected by having them performed on the same day. The doctor will propose a treatment plan based on the condition of your skin, so please feel free to consult with us.
Q: I am concerned because I have heard that there are risks such as blindness.
A. The risk of blindness from Botox between the eyebrows is extremely rare. It is mainly caused by accidental entry of the drug into blood vessels with hyaluronic acid injections, but Botox is a treatment in which a small amount is injected intramuscularly, and the chance of the drug entering a blood vessel is very small.
In addition, at Bibi Clinic, the doctor performs the procedure based on anatomical knowledge, identifying safe layers and directions to minimize risk.
Q: Can Botox between the eyebrows change the shape of the double fold?
A. Normally, Botox between the eyebrows does not significantly alter the bifocal line. However, if the muscles that lift the eyelids (eyelid elevators) are weak or if the eyelids are droopy, the eyelids may feel heavier due to the restricted movement of the eyebrows.
Even in such cases, Bibi Clinic will check the condition of the eyelids and the movement of the facial muscles in advance, and make detailed adjustments to the injection position and volume as necessary.
Botox between the eyebrows for a softer, gentler look
Botox between the eyebrows can soften and tone facial expressions that tend to look scary in a short procedure. Injecting small amounts of Botox by assessing the movement of the muscles allows for a natural-looking result.
At Bibi Clinic, we perform procedures while carefully balancing the facial expressions of each individual. If you are in Bangkok, Thailand, and wish to have a "kinder impression" or "prevent the appearance of aging," please feel free to contact us for a consultation.
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